What is NAD IV Therapy?

NAD⁺ (nicotinamide adenine dinucleotide) is an essential coenzyme found in every cell of the human body. Often called the “metabolic spark plug,” it plays a critical role in cellular function and energy production. Without adequate NAD⁺, cells cannot perform at their best.

Over time — particularly with aging, chronic stress, or illness — natural NAD⁺ levels decline. This reduction is now recognized as a key biomarker of aging and is linked to fatigue, cognitive decline, slower metabolism, and greater vulnerability to disease.

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Why is NAD+ IV Therapy So Important?

Inflammation Control & Immune Modulation

NAD⁺ supports mitochondrial health and helps regulate immune cell activity, playing a vital role in controlling inflammation. Since chronic inflammation is a root cause of many illnesses — from cardiovascular disease to neurodegenerative disorders — optimizing NAD⁺ levels can promote a healthier, more balanced immune response.

DNA Repair & Cellular Longevity

NAD⁺ activates key enzymes such as PARPs and sirtuins, which play a vital role in DNA repair and protecting cells from oxidative stress. By supporting these processes, NAD⁺ helps preserve the integrity of your genetic code, reduce inflammation, and regulate cellular aging. Sirtuins, in particular, are being widely studied for their potential to extend lifespan and protect against age-related diseases.

Energy Production at the Cellular Level

NAD⁺ is a critical coenzyme that helps convert the food you eat into usable cellular energy. It plays a key role in redox reactions, transporting electrons during the production of ATP (adenosine triphosphate) within the mitochondria. Without adequate NAD⁺, cells cannot efficiently generate energy — resulting in fatigue, muscle weakness, and reduced endurance.

Brain Function & Cognitive Performance

The brain is one of the body’s most energy-demanding organs, and it relies heavily on NAD⁺ to operate at peak performance. Higher NAD⁺ levels are associated with sharper memory, faster cognitive processing, improved focus, and even protection against neurodegenerative diseases such as Alzheimer’s.

Metabolic Health & Detoxification

NAD⁺ plays a key role in vital metabolic processes such as fat burning, insulin sensitivity, and liver detoxification. With sufficient NAD⁺ levels, the body is better able to metabolize glucose, eliminate toxins, and maintain a healthier, more balanced metabolic state.

NAD+ Frequently Asked Questions

How long does an NAD therapy session take?

On average, a single NAD therapy session lasts about 90 minutes.

Will I need to plan for any downtime after NAD therapy?

There is no downtime needed after NAD therapy. You will be able to return to all your normal activities following your appointment.

Is NAD therapy painful?

NAD therapy is not painful. The needle used for the IV is not large and is gently inserted. There are no painful side effects after treatment either.

How long before I notice a difference with NAD⁺ therapy?

Many clients begin to notice subtle improvements, such as increased energy, improved mental clarity, and better mood within just a few hours of their first infusion. This varies by individual, depending on baseline NAD⁺ levels and overall health. For those dealing with fatigue, brain fog, or chronic stress, the first few sessions often feel like a “reset” for the body and mind. While some benefits may be immediate, the most profound, long-lasting effects are typically experienced after a series of treatments as your cells begin to repair and restore function at a deeper level.

How often should I receive NAD⁺ therapy?

Frequency depends on your goals and current health status. For those seeking rapid improvement in symptoms, such as chronic fatigue, burnout, or detox support, we may recommend a loading phase of 3 to 5 infusions over 1–2 weeks. After that, most clients transition to a maintenance plan, with 1 to 2 infusions per month to support ongoing energy, cognition, and cellular health. Our providers will work with you to create a customized protocol based on your lifestyle, goals, and how your body responds to treatment.

Can I combine NAD⁺ with other wellness treatments?

Absolutely—and doing so may even enhance your results. NAD⁺ therapy works synergistically with a variety of other treatments offered at Aviva Infusions, including:

  • IV vitamin therapy to replenish essential nutrients and electrolytes
  • Glutathione infusions for antioxidant support and detoxification
  • Ketamine infusions for mood and mental health optimization
  • Weight loss programs that focus on metabolic restoration and energy support

Combining treatments can offer a more comprehensive approach to health and healing, particularly for those looking to boost physical performance, accelerate recovery, or address multiple wellness concerns at once. During your consultation, we’ll help you choose the ideal combination for your needs.